三氯杀螨醇对大型溞的毒性和环境雌激素效应

刘永梅, 陈伟, 李敦海, 刘永定

刘永梅, 陈伟, 李敦海, 刘永定. 三氯杀螨醇对大型溞的毒性和环境雌激素效应[J]. 水生生物学报, 2004, 28(3): 330-332.
引用本文: 刘永梅, 陈伟, 李敦海, 刘永定. 三氯杀螨醇对大型溞的毒性和环境雌激素效应[J]. 水生生物学报, 2004, 28(3): 330-332.
Liu Yong Mei, CHEN Wei, LI Dun Hai, LIU Yong Ding. REPRODUCTION TOXICITY AND ESTROGENIC EFFECTS OF DICOFOL TO DAPHNIA MAGNA[J]. ACTA HYDROBIOLOGICA SINICA, 2004, 28(3): 330-332.
Citation: Liu Yong Mei, CHEN Wei, LI Dun Hai, LIU Yong Ding. REPRODUCTION TOXICITY AND ESTROGENIC EFFECTS OF DICOFOL TO DAPHNIA MAGNA[J]. ACTA HYDROBIOLOGICA SINICA, 2004, 28(3): 330-332.

三氯杀螨醇对大型溞的毒性和环境雌激素效应

基金项目: 

中国科学院知识创新工程重大项目(KZCX1-SW-12)

国家重大环境课题"滇池蓝藻水华污染控制技术研究"(K99-05-35-01)

973项目(2202CB412300)

中国科学院方向性创新课题(220316)资助

REPRODUCTION TOXICITY AND ESTROGENIC EFFECTS OF DICOFOL TO DAPHNIA MAGNA

  • 摘要: 三氯杀螨醇是DDT被禁用以后出现的替代品,在很多国家包括中国在内被广泛用作果树、棉花等的杀螨剂,对高等动物的急性口服毒性很低,但它的慢性毒性较大。已有报道显示由DDT合成而来的三氯杀螨醇可使美国红隼的蛋壳变薄,与某些野生动物如佛罗里达湖中鳄鱼雌性化具相关性,甚至导致人体某些恶性肿瘤等。由于三氯杀螨醇性质非常稳定,残留期长,所以过去对该农药研究热点主要是在蔬菜、果品等食品中的残留及降解动态,而对水生生物的毒性尚未见报道,而且对其雌激素活性的报道仅限于小鼠子宫增重法等活体实验方法,周期长且由于生物个体差异等造成灵敏度低。
  • [1] Donald R,Clark J R,Spann J W,et al.Dicofol(Kelthane)-induced eggshell thinning in captive American kestrels [J].Environmental Toxicology and Chemistry,1989,9(8):1063-1069[2] Margie P A,Testing deadline for encocrine disrupters.[J].EnvironSci Tech,1996,30(12):540A-544SA[3] Qiu D R,Wu Z B.Effects of Environmental Estrogens on Animals and Humans [J].Acta Hydrobiologica Sinica,1997,21(4):365-374.[邱东茹.吴振斌.环境雌激素对动物和人体的影响及其作用机制.水生生物学报,1997,21(4):365-374][4] Zhao B S,et al.Bioassay of estrogenic effect of dicofol using uterine weight method in mice[J].Acta Scientiae Circumstantiae,2000,20(2):244-247.[赵炳顺等.小鼠子宫增重法检测国产三氯杀螨醇的雌激素生物活性.环境科学学报,2000,20(2):244-247][5] Wu W Z,Wang J X,et al.Recombinant gene yeast for assaying environmental estrogen pollutants[J].China Environmental Science,2002,22(1):60-63.[吴文忠,王敬贤等.重组基因酵母检测环境类雌激素污染物.中国环境科学,2002,22(1):60-63][6] Rehmann K,Wu W Z,Chen J,et al.Xenooestrogens in unexpected places-First results from the application of a yeast estrogen assay on non aqueous environmental samples[J].Industrial Toxicology,1999,307:129-131[7] Routledge E J,Sumoter J P.Estrogenic activity of surfactants and some of their degradation products assessed using a recombinant yeast screen[J].Environ Toxical and Chem.,1996,15(3):241-248[8] Sun M J,Zhang Y Y,Cai J P.Preliminary study of breeding and biology of Daphnia magna HB,a high-tempreture-resistant species[J].Acta Hydrobiologica Sinica,1991,15(2):166-173.[孙美娟,张甬元,蔡俊鹏.一种耐高温大型NFDB8HB的培养和生物学的初步研究.水生生物学报,1991,15(2):166-173][9] Wang D M.Wang M X,Luo S Y,et al.Mannual of inspecting on hydrobiology[M].Nanjing:Southeast university press,1993.44-45[王德铭,王明霞,罗森源等.水生生物监测手册.南京:东南大学出版社,1993.44-45][10] Rehman K,Schran K W,Ketterup A.Applicability of a yeast estrogen screen for the detection of oestrogen-like activities in environmental spmples[J].Chemosphere.1999,38(14):3303-3312[11] Vonier F M,Crain D A,Mclachlan J A,et al.Interaction of environmental chemicals with the estrogen progesterone receptors from the oviduct of the American alligator[J].Environ Health perspect,1996,104:1318-1322

    Donald R,Clark J R,Spann J W,et al.Dicofol(Kelthane)-induced eggshell thinning in captive American kestrels [J].Environmental Toxicology and Chemistry,1989,9(8):1063-1069[2] Margie P A,Testing deadline for encocrine disrupters.[J].EnvironSci Tech,1996,30(12):540A-544SA[3] Qiu D R,Wu Z B.Effects of Environmental Estrogens on Animals and Humans [J].Acta Hydrobiologica Sinica,1997,21(4):365-374.[邱东茹.吴振斌.环境雌激素对动物和人体的影响及其作用机制.水生生物学报,1997,21(4):365-374][4] Zhao B S,et al.Bioassay of estrogenic effect of dicofol using uterine weight method in mice[J].Acta Scientiae Circumstantiae,2000,20(2):244-247.[赵炳顺等.小鼠子宫增重法检测国产三氯杀螨醇的雌激素生物活性.环境科学学报,2000,20(2):244-247][5] Wu W Z,Wang J X,et al.Recombinant gene yeast for assaying environmental estrogen pollutants[J].China Environmental Science,2002,22(1):60-63.[吴文忠,王敬贤等.重组基因酵母检测环境类雌激素污染物.中国环境科学,2002,22(1):60-63][6] Rehmann K,Wu W Z,Chen J,et al.Xenooestrogens in unexpected places-First results from the application of a yeast estrogen assay on non aqueous environmental samples[J].Industrial Toxicology,1999,307:129-131[7] Routledge E J,Sumoter J P.Estrogenic activity of surfactants and some of their degradation products assessed using a recombinant yeast screen[J].Environ Toxical and Chem.,1996,15(3):241-248[8] Sun M J,Zhang Y Y,Cai J P.Preliminary study of breeding and biology of Daphnia magna HB,a high-tempreture-resistant species[J].Acta Hydrobiologica Sinica,1991,15(2):166-173.[孙美娟,张甬元,蔡俊鹏.一种耐高温大型NFDB8HB的培养和生物学的初步研究.水生生物学报,1991,15(2):166-173][9] Wang D M.Wang M X,Luo S Y,et al.Mannual of inspecting on hydrobiology[M].Nanjing:Southeast university press,1993.44-45[王德铭,王明霞,罗森源等.水生生物监测手册.南京:东南大学出版社,1993.44-45][10] Rehman K,Schran K W,Ketterup A.Applicability of a yeast estrogen screen for the detection of oestrogen-like activities in environmental spmples[J].Chemosphere.1999,38(14):3303-3312[11] Vonier F M,Crain D A,Mclachlan J A,et al.Interaction of environmental chemicals with the estrogen progesterone receptors from the oviduct of the American alligator[J].Environ Health perspect,1996,104:1318-1322

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出版历程
  • 收稿日期:  2003-03-01
  • 修回日期:  2003-05-09
  • 发布日期:  2004-05-24

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