Abstract: An 8-week feeding experiment was conducted to evaluate the effect of dietary canola meal (CM) levels on growth, feed utilization and some blood physiological-biochemical indices in juvenile black carp initial average weight of (5.77 ?0.05) g. The inclusion levels of CM were 0 (control), 11%, 22%, 33% and 44%, to replace 0, 25%, 50%, 75% and 100% of soybean meal (SBM), respectively. Each diet was randomly fed to triplicate groups of 25 fishes per tank (300 L). Fish were fed twice daily by hand at a rate of 3% -5% of body weight during eight weeks. The results showed that fish fed the diet with CM levels more than 11% showed relatively lower SGR, the activities of protease, amylase, lipase in intestine and apparent digestibility coefficients of dry matter and protein than those fed the control diet (PPPP<0.05), AST in serum were significantly higher in fish fed diets with CM level up to 33% and 44% levels than those fed control diet. No significant differences in body moisture and protein contents were observed among dietary treatments. Declining body lipid content and increasing body ash content were observed with increasing dietary CM level. The VR increased with the increasing dietary CM level and HSI first significantly increased and then reduced. Based on these observations above, more than 11% dietary CM level could decrease growth, immunity and liver function for juvenile black carp.